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Complex Regional Pain Syndrome

What are the symptoms and causes of CRPS and how can it be treated?

What is complex regional pain syndrome (CRPS)?

Complex regional pain syndrome (CRPS) is a chronic pain condition that can develop after an injury or surgery, or it can also occur without a clear cause. It is characterised by severe pain, typically in an arm or leg, and is often accompanied by changes in skin colour, temperature and swelling.

CRPS Type I and Type II—understanding the differences

There are two types of CRPS:

CRPS Type I


  • Develops after minor injuries or surgeries without nerve damage
  • Accounts for 90% of cases
  • is also known as reflex sympathetic dystrophy

CRPS Type II


  • Linked to specific nerve injuries
  • It Has similar symptoms to Type I and is also known as causalgia

The exact cause is unclear, but it involves an abnormal healing process.

 Severe Pain

Severe pain
Often described as burning or aching, usually worse than expected from the original injury.

 Sensitivity icon

Sensitivity
Extreme sensitivity to touch, pain from even light contact (allodynia).

icon temperature change

Color and temperature changes
Change in skin colour, e.g., becoming red or blue and feeling warmer or cooler than the other limb.

 Stiffness icon

Swelling
The affected area may swell due to fluid buildup.

 Stiffness icon

Movement issues
Stiffness, weakness and decreased range of motion in the limb.

Abnormal Hair icon

Abnormal hair and nail growth
Hair and nails on the affected limb may grow differently than those on the other limb.

In general, CRPS-I and CRPS-II have many symptoms in common, but they differ in one key way: CRPS-II involves a confirmed nerve injury, while CRPS-I does not. People with CRPS-I may experience pain that spreads more widely, while in CRPS-II, the pain and motor issues are often more focused around the injured nerve.

Key factors of CRPS include































Excessive and persistent inflammation after an injury, leading to nerve sensitisation and heightened pain response.

Antibodies targeting nerve cells may play a role.

Stress, anxiety and depression can amplify pain perception and result from chronic pain.

Treatment options for CRPS

CRPS is a complex condition that affects individuals differently. A combination of treatments is often the best approach, and early intervention can make a significant difference in managing symptoms and improving quality of life.

Pain Relievers: Over-the-counter medications can alleviate mild pain, while doctors may prescribe stronger medications for more severe pain.

Nerve Pain Medications: Some medications originally designed for seizures, like gabapentin and pregabalin, can help reduce pain caused by nerve issues.

Antidepressants: Certain antidepressants can help with chronic pain, even if the individual isn't depressed.

Corticosteroids: These can help reduce swelling and inflammation in the affected area.

Topical Treatments: Creams that numb the area or contain natural ingredients like capsaicin (from chili peppers) may provide relief when applied to the skin.

Physical Rehabilitation Exercises: A structured physical therapy program can help improve mobility, strength, and function in the affected limb.

Daily Living Skills: Occupational therapy can assist people in managing everyday tasks and adapting their environment to make life easier.

Pain Management Counseling: Working with a pain psychologist can assist in developing coping strategies and improving overall wellbeing.

Cognitive Behavioral Therapy (CBT): This type of therapy can teach strategies to manage pain and reduce stress.

Acupuncture: Some people find relief through acupuncture, which involves inserting thin needles into specific points on the body.

TENS Therapy: This method uses low-voltage electrical currents to help reduce pain.

Mindfulness Techniques: Practices like meditation and relaxation exercises can help individuals manage pain better.

Nerve Blocks: Injection of anesthetics or steroids around specific nerves can help alleviate pain and inflammation.

Spinal Cord Stimulation: This is a minimally-invasive option for managing chronic pain and it involves implanting a small device near the spinal cord that sends electrical impulses to interfere with pain signals traveling to the brain.

Learn more about Spinal Cord Stimulation >>

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